RAF Typhoon jets have conducted a mission with France's air force in a joint strike on an subterranean weapons facility in Syrian territory operated by the IS group, per a report from the British defence ministry.
The location, pinpointed through surveillance, was thought to be housing weapons and explosive materials, the announcement noted, and was situated in hills just north of the historic site of Palmyra in central Syria.
"Our fighter planes used laser-guided Paveway IV weapons to target a series of approach shafts down to the depot... initial indications suggest the target was engaged successfully," the MoD said.
There was no evidence of any civilian impact in the operation on Saturday evening and all the aircraft made a safe return, the defence officials confirmed.
The Typhoon FGR4s were supported by a Voyager refuelling tanker.
Daesh - also known as the so-called Islamic State - enforced jihadist rule over large swathes of Iraq and Syria until 2019.
"This action shows British leadership, and commitment to operate in unison with allied nations, to eliminate any revival of Daesh and their violent and radical beliefs in the area," Britain's Defence Chief the minister said.
UK warplanes have carried out overwatch operations over Syrian airspace to "prevent any efforts to regroup" of the group after its routing at the climactic battle in Baghuz in the year 2019, the ministry said.
"I extend gratitude to all the members of the UK armed forces involved in this operation for their skill and their valour," he added. "They were among numerous UK service members deployed over the festive period. This operation, to take out terrorist threats who pose a risk to our way of life, demonstrates how our armed forces are prepared to act, all year round, keeping Britain secure within its borders and strong abroad."
During December, the US military executed what it called a "large-scale strike" targeting Daesh sites in the country, subsequent to an assault claimed the lives of two US servicemembers and a local interpreter in Palmyra.
The United Nations says IS still boasts an estimated 5,000 to 7,000 militants in Iraq and Syria.